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In Search of the Double Helix, by John Gribbin
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UNRAVELING THE MYSTERY OF LIFE ON EARTH
The search began with Darwin's historic voyage on the Beagle and it continues today in the laboratories of the genetic engineers. How did life on earth begin? What is the key to evolution that insures only the fittest survive? How do we differ from other species? And how might tomorrow's scientists read—and alter—the biological blueprint to eliminate disease, birth defects, and even create new life forms?
Acclaimed science writer John Gribbin draws on his expertise in quantum physics to tell the story of one of the greatest and most dramatic of scientific discoveries. His search for the elusive double helix takes us through the twists and turns of disappointment and discovery on a fascinating quest to the source of life itself. In clear, straightforward language, he presents the lives and thoughts of the men and women whose pioneering work in physics, biology, genetics, and chemistry combined to provide a basic understanding of how life evolved—and continues to evolve—on earth. He follows the trail of discovery from X-rays, mutations, quantum mechanics, the molecular clock, and sexual reproduction—all the way to the innermost workings of the human cell. And he shows how modern science first learned to "crack" the genetic code of life and the profound consequences this new knowledge will have on our future.
- Sales Rank: #466965 in eBooks
- Published on: 2015-03-30
- Released on: 2015-03-30
- Format: Kindle eBook
About the Author
Dr John Gribbin trained as an astrophysicist at the University of Cambridge before becoming a full-time science writer. He has worked for the science journal Nature, and the magazine New Scientist and has contributed articles on science topics to The Times, the Guardian and the Independent, and has made several acclaimed science series for BBC Radio 4. John Gribbin has received awards for his writing in both Britain and the United States and is currently a visiting Fellow in astronomy at the University of Sussex. His many books include In Search of Schrödinger’s Cat, Stephen Hawking: A Life in Science (with Michael White) and In Search of SUSY. John Gribbin is also the author of several science fiction works including Innervisions. He is married with two sons and lives in East Sussex. More books from John Gribbin are available at: http://ReAnimus.com/authors/johngribbin
Most helpful customer reviews
2 of 2 people found the following review helpful.
Quantum Chemistry
By Normand Hamel
In the introduction the author tells the following anecdote: I will always be grateful to my younger son, Ben, for a comment he made when I was halfway through the first draft, with no end to the project in sight, and assailed by the usual doubts authors have about whether they are wasting their time. He picked up a stack of printout, sat quietly reading it for more than an hour, then turned to his mother with these words: 'I like this book. It's really interesting. Even if you don't understand all the words, it's still like a story book.'
Well, that's exactly the kind of book I thought it would be when I started to read "In Search of the Double Helix". And because of the title I thought it was specifically about the story of the discovery made by Francis Crick and James Watson: the identification of the DNA molecule, the so-called molecule of life. But I quickly realized that this fascinating story comprises only one chapter. It is the longest chapter but still covers less than 20% of the book. So I thought it would be useful for potential readers to know the exact content of the book. Here is a summary of what is covered in each chapter.
Chapter 1 is a review of Darwin's theory (20 pages).
Chapter 2 offers a summary of Mendel's findings (29 pages).
Chapter 3 is about sexual reproduction at the cellular level (27 pages).
Chapter 4 covers the basic concepts of Quantum Physics (30 pages).
Chapter 5 introduces the reader to the basic principles of Quantum Chemistry (26 pages).
Chapter 6 explains what Molecular Biology is all about (49 pages).
Chapter 7 tells the story of the race to identify the structure of the DNA molecule (63 pages).
Chapter 8 presents a survey of the developments that followed the DNA discovery (40 pages).
Chapter 9 is dedicated to the subject of jumping genes (26 pages).
Chapter 10 gives a summary of the previous chapters (29 pages).
In this book John Gribbin tries to make the case that quantum physics is at the heart of DNA. But we could only say so if for example a gene mutation was a pure quantum phenomenon, like say the decay of an atom. But it isn't. The science behind DNA is called molecular biology and it is is based on quantum chemistry principles, which are themselves derived from the laws of quantum physics. In my opinion it would be more appropriate, and less confusing, to say that the science of DNA is based on chemistry. And indeed you will find quite a bit of chemistry in this book.
For many readers the most interesting chapter will be the one that tells the story of DNA with Crick and Watson. But after reading other accounts of this story, in for example "The Double Helix" and "The Dark Lady of DNA", I was slightly disappointed. I expected, but did not find, the same clarity as in Gribbin's other books like "In Search of Schrödinger's Cat" and "In Search of the Big Bang", among others. On the other hand I have read in the concluding pages of that chapter the best account of how the discovery was published. Gribbin's view on this is extremely lucid and helped me to better understand what had been going on until the discovery was made.
Overall this book is quite heavy on the science. Perhaps unnecessarily so. For at times I had the impression the author was going too deep in various subjects that were not directly related to DNA. But I would not hesitate to recommend it to anyone preparing for a career in science.
2 of 2 people found the following review helpful.
The most significant book for me in decades--
By Tintinnabulation
I stumbled across the book "In Search of the Double Helix" a year ago. I got it from the public library. To me it is so rewarding to go over the material again and again-- each time I gain more. I had to get my own copy. What a treasure! We have gone so far in the understanding of not only evolution, cell microbiology, quantum physics, DNA....yet, we have so much more to go. Before you cash in your chips, get the book "in Search of the Double Helix".
0 of 0 people found the following review helpful.
SIMPLE ENOUGH TO BE BRILLIANT
By cebepe
This is a terrific book for an interested non-scientific person. The author writes well and intelligently, but simply enough for us to understand these world-changing developments in the quantum basis of DNA.
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